Parkinson’s disease currently affects about 10 million people worldwide, with no cure or treatment. Thanks to an international team of scientists, including Professor Kwang-Soo Kim in the US and Associate Professor Yoon Ho Sup in Singapore, this may change. The team identified two anti-malaria drugs, Chloroquine and Armodiaquine as a potential treatment. The drugs activate Nurr1, a class of proteins found in the brain that protect the brain’s ability to generate dopamine neurons which affect motor control and movement of muscles in the body. Chloroquine is no longer used to treat malaria, as the parasite grew resistant to it. However, both drugs were effective in animal studies, and the researchers intend to carry out clinical trials to confirm results.
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