drug repurposing

/Tag:drug repurposing

The anti-obesity drug Belviq may be repurposed for treatment of cocaine abuse

Since its approval by the FDA in 2013, Belviq® has been used to successfully treat patients with obesity by acting on serotonin receptors in the brain to increase feelings of satiety. However, the drug was recently used in studies at the University of Texas on rhesus monkeys who were addicted to cocaine, as the addiction/reward pathway is closely […]

Tapeworm drug deemed effective at curbing MRSA

Methicillin-resistant staphylococcus aureus (MRSA) is an antibiotic-resistant infection that has historically been difficult to treat. However, studies at Brown University and Rhode Island hospitals have proven that an FDA-approved drug used to treat tapeworm was able to curb growth of MRSA bacteria in vitro and in nematode populations. Since it has already been approved and its […]

Repurposed experimental cancer drug restores brain function in mouse models of Alzheimer’s disease

Currently undergoing clinical trials, the drug saracatinib, which was originally developed for cancer, is being repurposed as a treatment for Alzheimer’s. Animal testing at the Yale University School of Medicine showed a decrease in memory loss and reversal of brain damage caused by the mouse model of the disease. After obtaining the drug from AstraZeneca, researchers were able […]

Viagra may help cure malaria, research suggests

Viagra, which was originally created to treat chest pain and later marketed for erectile dysfunction, has been repurposed before. But recent research has discovered yet another possible use for the drug: treatment of malaria. The most deadly strain of the disease causes harm by causing cells to secrete certain “camouflage” chemicals that fool the immune […]

Olaparib halts tumor growth in advanced prostate cancer

A fairly new drug called olaparib was approved by the FDA in 2014 to treat ovarian cancer in women with BRCA mutations. However, recent studies have shown that different types of cancer can be treated with this drug, and that the target demographic extends beyond those with the specific genetic mutation. In a phase II […]

Saccharin could sweeten the deal for cancer-fighting drugs

In an exciting new discovery that could bring about significant progress in cancer research, it appears that saccharin, an artificial sweetener, can bind selectively to a protein involved in many aggressive forms of cancer. Since the protein is similar to many others that are abundant in the body, finding a way to target this specific […]

Athlete’s foot drug may be MS therapy

Animal research has shown that common topical drugs used to treat eczema and athlete’s foot can encourage regrowth of myelin coating in damaged nerves, which may slow or stop disease progression in multiple sclerosis patients. Clinical trials have yet to begin, but research on human cells in vitro has been promising, and researchers at Case Western Reserve […]