In the News

New treatment for common incurable eye condition

At the Israeli Society for Vision and Eye Research (ISVER) conference, the MedInsight Research Institute and Center for Drug Repurposing at Ariel University presented the latest findings on positive user-reported outcomes of the repurposed drug dipyridamole in treating pterygium and related dry-eye symptoms.

Pterygium, or Surfer’s Eye, is a benign growth that affects 10% of the […]

Scientists are closer than ever to a single antidote for 28 common snakebite venoms

If you get bitten by a venomous snake, there are medicines that can help, but these antivenins are specific to each species of snake. Researchers in the US are announcing that they’re in the early stages of developing a snakebite antidote that can fight 28 common venoms and be administered out in the field without the […]

Novel drug repurposing method reveals two drugs effective for bacterial, fungal infections

Mohamed Seleem, an associate professor of microbiology in Purdue’s College of Veterinary Medicine, used novel drug repurposing methods to discover two drugs that could have significant promise as a potent antimicrobial agent for treatment of both superficial and invasive infections. Through his research and studies he has identified auranofin and ebselen as potent antimicrobial agents […]

Using old drugs to treat new viruses

A group of drugs already in everyday use to treat psychosis or depression may also be used to defeat deadly and emerging viruses, according to new research led by the University of Leeds. The virus the research focused on was the Bunyavirus family, which includes lethal human pathogens such as Hantaviruses and Crimean-Congo haemorrhagic fever virus.

Dr […]

Drug Repurposing Yields Hope for Reversing Effects of Parkinson’s

Preliminary findings from a small-scale study done by Georgetown University Medical Center researches indicate that a medication approved to treat leukemia may halt or reverse the progression of Parkinson’s disease and Lewy body dementia.

Dr. Moussa states that their work “has been focused on repositioning this already-FDA-approved drug, that we now have a good safety profile to […]

Randy Forbes: Trailblazing a cure

Randy Forbes introduces us to Dr.  Emil Freireich, who in 1995 took on the challenge of Children’s Leukemia. Dr. Freireich wondered if combining several chemotherapy treatments simultaneously would increase the success rate of remissions.

Over the course of several trials, Dr. Freireich, along with a colleague, discovered a multi-drug treatment for leukemia. Their discovery led to cures that […]

International CTCA study shows statins could be effective against small cell lung cancer

Small cell lung cancer is one of the most aggressive types of cancer, and in a recent study statins, a class of drugs primarily used to lower cholesterol in patients at risk for heart disease, appeared to provide an increase in overall survival for those cancer patients who received them.

This study specifically examined late-stage SCLC patients who […]

“Rescued” drug could be safer treatment for Bipolar Disorder

The drug Ebselen was originally developed for strokes,but destined for the scrap heap.  It has been rescued by Oxford scientists, who may have found it a new role in treating bipolar disorder.

A team from Oxford University used a database of ‘failed’ drugs, found to be safe but ineffective for their proposed use, to identify Ebselen as a […]

One-cent wonder drug?

“Drug repurposing can potentially see a cheap, good, and powerful drug like aspirin prevent and even treat cancer effectively,” said Dr Toh Han Chong, deputy director of National Cancer Centre, Singapore. He and Dr. Chia are leading the first global clinical trial, named Ascolt, to see if aspirin can stop the recurrence of cancer after […]

Arthritis Drug Successful in Blood Cancer Treatment

The rheumatoid arthritis drug methotrexate, has been show to be a cheaper and effective alternative for blood cancer sufferers. Researchers have found that methotrexate can have the same effect on patients with blood disorders that the drug Ruxolitinib has. Because methotrexate is a World Health Organization ‘Essential Medicine,’ this also means that this well understood drug could […]